Effects of inducible nitric oxide synthase on mechanism of osteoarthritis
- VernacularTitle:诱生型一氧化氮合酶在骨关节炎发病机制中的作用探讨
- Author:
Meirong LI
- Publication Type:Journal Article
- Keywords:
Osteoarthritis;
Nitric-oxide synthase
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(11):1784-1785,插二
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression of inducible nitric oxide synthase (iNOS) in synovium of osteoarthritis and to investigate the relationship with the disease.Methods iNOS expression is investigated by means of immunohistochemical assay.Results By immunohistochemical assay , we found that there are significant expression of iNOS in synovium of osteoarthritis patients than that of control.Conclusion In OA ,there are high expression of iNOS in synovium ,so we concluded that iNOS may mediate the pathogenesis and development of OA.
