Effects and significance of essential fatty acids on contents of eicosapentaenoic acid and docosahexaenoic acid in rat brain tissues
- VernacularTitle:必需脂肪酸对大鼠脑组织中EPA、DHA含量的影响及意义
- Author:
Kan ZHANG
;
Lin ZENG
;
Zaiyun LONG
;
Yuan LIU
;
Yamin WU
;
Cuilan TAO
;
Fengc HE
- Publication Type:Journal Article
- Keywords:
essential fatty acids;
eicosapentaenoic acid;
docosahexaenoic acid;
high performance liquid chromatography
- From:Journal of Third Military Medical University
2002;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of essential fatty acids(EFA)on the contents of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in the brain tissues of rats. Methods A total of 30 neonatal rats, 1 month old, were randomly divided into normal, EFA deficiency and fish oil supplement groups and given different feeding stuff for 3 months respectively. The contents of EPA and DHA in brain tissues were determined by high performance liquid chromatography (HPLC). Results As compared with normal group, the contents of EPA and DHA in EFA deficient group were significantly decreased(P
