Alternative splicing of gene transcription and its progress in clinical pharmacology
- VernacularTitle:基因转录另路剪接及其在临床药理学的研究进展
- Author:
Lifang DUAN
;
Honghao ZHOU
- Publication Type:Journal Article
- Keywords:
alternative splicing;
regulation mechanisn clinical pharmacology
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Alternative splicing is strictly affected by special cell or tissue and the stage of development so that it plays a vital role in development, cell or tissue differentiation and their function, accordingly, abnormal splicing will cause the functional disorder of body, and heritable diseases. Currently, the investigation on regulation of alternative splicing and its mechanism, function of its products and how to apply it into clinical practices is one of the extremely important area of pharmacogenomics
