The function of Th and dendritic cells in patients with different hepatitis B virus genotypes
- VernacularTitle:应用干扰RNA体外抑制严重急性呼吸综合征冠状病毒N基因的表达
- Author:
Kai WANG
;
Qin LU
;
Liyan HAN
- Publication Type:Journal Article
- Keywords:
Hepatitis B, chronic;
T-lymphocytes, helper-inducer;
Genotype;
Dendritic cells;
Hepatitis B virus
- From:
Chinese Journal of Infectious Diseases
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the function difference of T helper cells(Th)and dendritic cells (DCs) in patients with different hepatitis B virus (HBV) genotypes. Methods IL-12,IL-2 and IL-4 released by Th was measured in 30 patients with different HBV genotypes. After DCs were differentiated and proliferated, DCs’ configuration and amounts were observed, and IL-12 released by DCs was measured in 20 patients. Then the data were statistical analyzed. Results IL-12, IL-2 and IL-4 were significantly higher in patients with hepatitis B than the controls (t=2.9272,t=2.7350,P
