STUDY ON REGULATION OF CHROMIUM ON GLUT4 EXPRESSION OF SKELETAL MUSCLE IN DIABETIC RATS
- VernacularTitle:铬对糖尿病大鼠骨骼肌GLUT4基因表达的影响
- Author:
Zhong SUN
;
Yuntang WU
;
Suping CHE
;
Xia WANG
;
Gang GUO
- Publication Type:Journal Article
- Keywords:
GLUT4;
diabetic rat;
RT-PCR;
gene clone;
chromium
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the regulation of chromium on the related gene expression of glucose metabolism in skeletal muscle in diabetic rats. Methods: cDNA fragments were cloned, sequenced from our former research and its homology analysis has been done. RT-PCR was performed using the primers designd according to the sequence of cDNA. Results: The sequence identities between Cr-3 and GLUT4 were 98%. The GLUT4 mRNA expression level of DM+Cr group was obviously lower than that of normal group (P
