Neurolymphomatosis, a case report
- VernacularTitle:神经淋巴瘤病一例报告
- Author:
Hongyan BI
;
Jia NA
;
Guiming ZANG
;
Wei ZHANG
;
Yu YUAN
- Publication Type:Journal Article
- Keywords:
Marek disease;
Polyneuropathy;
Biopsy
- From:
Journal of Peking University(Health Sciences)
2004;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Neurolymphomatosis(NL) is characterized by lymphomatous infiltration of the peripheral nervous system. We report a case of neurolymphomatosis(NL) which was confirmed by sural nerve biopsy. Sural nerve specimen from a 49-year-old female patient with weakness of limbs was examined with routine histochemical and immunohistochemistry staining, in which the first antibodies against CD3, CD20, CD45, CD45RO and CD68 were used. Numerous T-lymphoma cells invaded in the adipose tissue of epineurium of sural nerve. The nerve biopsy showed marked axonal degeneration of myelinated fibers. The clinical and histopathologic findings confirmed the diagnosis of neurolymphomatosis.
