Comparative proteomics studies on the serum of patients of colorectal cancer, LoVo cell suspension and HT29 cell culture fluid by use of SELDI TOF mass spectrometry
- VernacularTitle:结直肠癌患者血清与LoVo细胞、HT29细胞培养液比较蛋白质组学研究
- Author:
Chunfang GAO
;
Yanchun LIANG
;
Xiul WANG
- Publication Type:Journal Article
- Keywords:
colorectal neoplasms;
proteomics;
tumor markers, biological;
LoVo cells;
HT29 cells
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the specific proteomics between LoVo cells suspension, HT29 cells culture fluid and the serum of patients oof colorectal cancer. Methods serum of colorectal cancer, LoVo cells suspension and HT29 cells culture fluid were detected by IMAC3 chip and proteinchip reader (CipherGen Inc., VS). Results A protein at M/Z value 11731D was checked out in the LoVo cell suspension and the patients′ serum. No similar biomarkers were found in HT29 cell suspension and serum of colorectal cancer. Conclusion There existed similar biomarkers between LoVo cell suspension and serum of colorectal cancer
