Effect of Capsule- deficient strains CAP64 on apoptosis of mice microglia cell-line (N9) cell in vitro
- VernacularTitle:无荚膜隐球菌CAP64对小胶质细胞凋亡的影响
- Author:
Yang YANG
;
Wanqing LIAO
;
Hon XU
- Publication Type:Journal Article
- Keywords:
mice microglia cell line (N9) cell;
Cryptococcus;
CAP64;
apoptosis
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of capsule deficient strains CAP64 on apoptosis of mice microglia cell line (N9) cell in vitro . Methods N9 cells were co cultured with CAP64, the flow cytometry was employed to detect the N9 cellular apoptosis on different phase. Results The average apoptotic index of N9 after cultured for 2、4、8、16、24 hours with CAP64 were 9 33%、12 93%、15 37%、16 30% and 20 5%, respectively. There were significant differences between experimental group and control group. Conclusion Capsule deficient strains CAP64 can induce microglia cell line (N9) apoptosis
