Evaluation of PSP combined with chemotherapy in the treatment of malignant tumor patients
- VernacularTitle:云芝糖肽配合化疗对恶性肿瘤患者的评估
- Author:
Sihan LAI
;
Li YIN
;
Wenwen LI
;
Can XU
;
Yixi BAO
- Publication Type:Journal Article
- Keywords:
Polysacchariopeptide;
Malignant tumor;
System evaluation;
Randomized controlled trials
- From:
Chinese Journal of Immunology
2010;26(1):51-56,65
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the quality of life,peripheral blood and immune function of patients with malignant tumors treated by PSP.Methods: We searched MEDLINE,Pubmed and other databases by computer.We assessed the identified studies in order to include high quality studies.Results:A total of 7 into the study,701 cases of patients.Meta analysis showed that polysacchariopeptide treatment for patients with certain malignant tumors after chemotherapy might improve the quality of life.Polysacchariopeptide group combined with chemotherapy drugs might improve the white blood cells,hemoglobin,platelet compared to chemotherapy drugs or batyl alcohol drugs combined with chemotherapy.Polysacchariopeptide drug combined with chemotherapy may increase the CD_3~+ ,CD_4~+ ,CD_8~+ and CD_4~+/CD_8~+ ratio,and the NK cells was no significant difference.Conclusion:PSP combined with chemotherapy to treat malignant tumors has a certain effect.However,most of trials included in the review may be of low quality,therefore,it may be neccessity to conduct multi-center randomized-controlled trials of high quality.
