Therapeutic effects of mycophenolate mofetil in treating 16 cases of refractory idiopathic thrombocytopenic purpura.
- VernacularTitle:霉酚酸酯治疗难治性特发性血小板减少性紫癜16例疗效观察
- Author:
Shaojie HONG
;
Xiaoling TANG
- Publication Type:Journal Article
- Keywords:
Mycophenolate mofetil Purpura,thrombocytopenic,idiopathic Treatment
- From:
Chinese Journal of Practical Internal Medicine
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic effects of mycophenolate mofetil(MMF) in the treatment of refractory idiopathic thrombocytopenic purpura(ITP).Methods 16 refractory ITP patients were treated with MMF (1.0～1.5g/d),which were given in divided doses for three months as one course;the patients with significant therapeutic effect were given the dose for another three months and reduced by degree.Results Very effective results were obtained in 4 cases,striking improvement in 7,partial response in 1 and no response in 4.The total efficacy was 68.75%.The main side effect was observed as light digestive malaise.Conclusion MMF has striking therapeutic effect in treating refractory ITP with little side effect and can be used as an effective way of treatment.
