Recent advances in research on survivin and its moecular antagonists
- VernacularTitle:肿瘤治疗靶点survivin及其分子拮抗剂的研究进展
- Author:
Weilin HUANG
;
Xiangjun ZHOU
;
Yongxiang WANG
- Publication Type:Journal Article
- Keywords:
survivin;
cancer;
target;
molecular antagonist
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Survivin is a member of the IAP family, which has been shown to localize to various components of the mitotic apparatus. Survivin is not only an apoptosis inhibitor, but a mitotic regulator as well. Survivin is Absolutely undetectable in normal tissues, but over-expressed in all the most common human cancers. Survivin is considered as an important target in cancer treatment, and the research on its molecular antagonists has gained encouraging achievements.
