Study advances of cytochome P450 sensitive to antihistamine drugs
- VernacularTitle:抗组胺药敏感性的细胞色素P450研究进展
- Author:
Yimin ZHANG
;
Naiping WANG
- Publication Type:Journal Article
- Keywords:
HP450;
cytochrome P450;
histamine;
H_1 receptor
- From:
Chinese Pharmacological Bulletin
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
HP450 has thecharacteristic of cytochrome P450 and sensitivity to antihistmine drugs.With distinct raiiable regularity in the diverse disease modes of the rat,and some relativity to the development of liver disease,the expression and transcription of the HP450s gene have all changed in the course of the liver cancer. HP450 is possibly regarded as a new index of diagnosing liver cancer and a new target site of preventing and treating liver cancer