Research progress in mechanisms of biocompatibility
10.3760/cma.j.issn.1673-4181.2011.01.014
- VernacularTitle:生物相容性材料作用机制研究进展
- Author:
Zhe DONG
;
Tingfei XI
- Publication Type:Journal Article
- Keywords:
Biocompatibility;
Interaction;
Biodegradation
- From:
International Journal of Biomedical Engineering
2011;34(1):-
- CountryChina
- Language:Chinese
-
Abstract:
The interaction of biomaterials and tissues has been the focus of biomaterial science for many years and formed the foundation of the subject of biocompatibility. The research about biomaterials provides better basis for biomedical devices by the understanding of biocompatibility phenomena. In this paper, over 50 years of experience with such devices is analysed and it is shown that, in the vast majority of circumstances, the sole requirement for biocompatibility in a medical device intended for long-term contact with the tissues of the human body is that no harm should be brought to those tissues. Only a few bio-active biomaterials has been applied successfully in clinics. This artical gives a review on the application of biomaterials in tissue engineering,sophisticated cells, drug and gene delivery systems and in biotechnology. Interactions between biomaterials and tissue components is discussed as well.