Binding capacity of aberrantly glycosylated serum IgA1 with human umbilical vein endothelial cells
- VernacularTitle:糖基化缺陷的血清IgA1与人脐静脉内皮细胞结合量的研究
- Author:
Junjun ZHANG
;
Feng YU
;
Lixia XU
;
Ying ZHANG
;
Minghui ZHAO
- Publication Type:Journal Article
- Keywords:
Glomerulonephritis, IgA;
Glycosylation;
Immunoglobulin A;
Endothelial cells;
Umbilical Veins
- From:
Journal of Peking University(Health Sciences)
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05), respectively. Conclusion: IgA1 could bind to HUVEC directly, and the binding capacities of DesIgA1 and Des/DeGalIgA1 to HUVEC were significantly higher than that of normal IgA1. Serum IgA1, especially deglycosylated IgA1, might play some role in vascular lesions of IgAN.
