Distribution of Helicobacter pylori in stomach before and after the administration of Lansoprazole
- VernacularTitle:兰索拉唑用药前后幽门螺杆菌在胃内分布的变化
- Author:
Zhu JIN
;
Xiuyun DONG
;
Sanren LIN
;
Simao YE
;
Liya ZHOU
;
Hongya CHENG
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Lansoprazole;
Gastritis
- From:
Journal of Peking University(Health Sciences)
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of the acid inhibitor-Lansoprazole on the distribution of Helicobacter pylori (H.pylori) in stomach. Methods: Biopsy specimens were taken from the duodenal ulcer patients who underwent gastroscopy before and after the treatment of Lansoprazole. The biopsy specimens were taken from the lesser curvature of the antrum and the greater curvature of the corpus respectively. H&E and Warthin-Starry staining were used for detecting the changing of active gastritis and the positive rate of H.pylori. Results: (1)The positive rates of H.pylori before treatment, 4 weeks after treatment and 3 months after treatment, in the lesser curvature of the antrum were 93.02%, 58.14%, and 86.05%, respectively. The positive rate and density of H.pylori 4 weeks after treatment were greatly decreased compared with those before treatment (P
