Protective effects of puerarin on CCl_4-induced acute hepatic injury in rats
- VernacularTitle:葛根素对CCl_4所致大鼠急性肝损伤的保护作用
- Author:
Chunjing ZHAO
;
Lai WEI
- Publication Type:Journal Article
- Keywords:
puerarin;
hepatic injury;
protective effect
- From:Journal of Third Military Medical University
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the protective effects of puerarin on CCl 4-induced acute hepatic injury of rats. Methods Acute hepatic injury model was induced by CCl 4. Before and after low-dose (40 mg/kg) or high-dose (200 mg/kg) of puerarin was given, the levels of AST, ALT in serum, and liver index, and SOD activity, MDA content in serum and liver tissue were measured. Liver pathological changes were also observed. Results Puerarin reduced the serum levels of AST, ALT obviously (P
