Protective effects of mycelium of cultured Cordyceps sinensis on testis in diabetic rats
- VernacularTitle:人工冬虫夏草菌丝体对糖尿病大鼠睾丸的保护作用
- Author:
Zhihong DENG
;
Xiaoyan LIN
;
Weimin LI
- Publication Type:Journal Article
- Keywords:
Cordyceps sinensis;
mycelium;
diabetes mellitus;
testis
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the protective effects of mycelium of cultured Cordyceps sinensis on testis in diabetic Wistar rats. Methods 21 rats were divided into control group(C), diabetes group(D) and treatment group (T) at random. Diabetic model was reproduced by intraperitoneal injection of alloxan. After having been treated with Jinshuibao capsule for 8 weeks, serum levels of glucose, insulin, testosterone and levels of high energy phosphate compound, MDA, SOD, GSH-Px, and ATPases in the testis were determined respectively. Results Compared with control group, testicular mitochondria showed lipid peroxidase injury, with disturbed energy metabolism, and the activity of ATPases was lowered. All the changes in serum and testes were improved when Jinshuibao capsule was given. Conclusion Mycelium of cultured Cordyceps sinensis might have protective effects on the testis in diabetic Wistar rats.
