A study of the relationship between plasma factor Ⅶ coagulant activity and features of insulin resistance as well as macrovascular complications in typ e 2 diabetes.
- VernacularTitle:2型糖尿病血浆凝血因子Ⅶ与胰岛素抵抗及大血管并发症关系的研究
- Author:
Zhanjian WANG
;
Shuguo HU
;
Xiaohua GUO
- Publication Type:Journal Article
- Keywords:
Factor Ⅶ Insulin resistance Diabetes Macrovascu lar complications
- From:
Chinese Journal of Practical Internal Medicine
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between l evels of FⅦc and features of IR as well as macrovascular complications in type 2 diabetes.Methods The 2001-10~2002-08 FⅦc levels were measured by a one -stage biological assay in patients with type 2 diabetes and controls.Results (1)Type 2 diabetic patients had significantly higher FⅦc than control subjects.(2)FⅦc levels were higher in the type 2 diabetes w ith macrovascular complications than in those without macrovascular complication s.(3)FⅦc levels correlated positively with most features of IR.Conclusion FⅦc levels are increased in type 2 diabetic pat ients.Elevated FⅦc may be an important sign of IR and may contribute to type 2 diabetes and its macrovascular diseases.
