Serum superoxide dismutase level and malondiadehyde level in subjects with different glucose tolerance.
- VernacularTitle:不同糖耐量者血清丙二醛及超氧化物歧化酶水平的变化
- Author:
Lihong WANG
;
Jing AI
;
Jinchao ZHANG
- Publication Type:Journal Article
- Keywords:
Oxidative stress Insulin resistance
- From:
Chinese Journal of Practical Internal Medicine
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the state of oxidative s tr ess in patients with different glucose tolerance and the relationship between ox idative stress and insulin resistance(IR).Methods The levels of serum superoxide dismutase (SOD) and malo ndiadehyde(MDA)were measured in subjects of controls,obesity,impaired glucose to lerance (IGT) and newly diagnosed type 2 diabetes mellitus(T2DM).Results Oxidative stress has already existed in obesity and IGT group.MDA level was negatively correlated with insulin sensitive index (ISI) an d SOD level was positively correlated with ISI(all P