Anti-inflammatory and antibacterial effects of total flavones of oldenlandia diffusa willd
- VernacularTitle:白花蛇舌草总黄酮的抗炎及抗菌作用
- Author:
Yuling WANG
;
Yan ZHANG
;
Ming FANG
;
Qianjin LI
;
Qing JIANG
;
Liang MING
- Publication Type:Journal Article
- Keywords:
total flavones of oldenlandia diffusa willd(FOD);
anti-inflammatory;
antibacterial
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study anti-inflammatory and antibacterial effects of total flavones of oldenlandia diffusa Willd(FOD).Methods The models of dimethylbenzene-induced ear swollen in mice,turpentine-induced granuloma pouch in rats,paw edema caused by egg white in rats,increased vascular permeability by acetic acid in mice and the antibacterial activity in vitro were used to study FOD. Results FOD(15、30 and 60 mg?kg~-1 )show a marked suppressive effect on dimethylbenzene-induced ear swollen and increased vascular permeability in mice. In addition,FOD(12、24 and 48 mg?kg~-1 ) could reduce the paws edema and the granuloma pouch in rats.On the other hand,FOD had significally bacteriostatic effects against eight kinds of bacterial in vitro, in which effect on coccus is superior to that on bacillus.Conclusion FOD has anti-inflammatory and antibacterial effects.
