Image fusion between ~(18)F-deoxyglucose-positron emission tomo graphy and CT in con for mal radiotherapy for non-small-cell lung carcinoma
- VernacularTitle:氟脱氧葡萄糖正电子发射型体层摄影术在非小细胞肺癌适形放疗中的应用研究
- Author:
Huiming YU
;
Jinming YU
;
Yunfang LIU
;
Xianguang ZHAO
;
Li MA
- Publication Type:Journal Article
- Keywords:
F-deoxyglucose;
Tomography,emission, positron;
Lung neoplasms/radiotherapy;
Radiotherapy,conformal
- From:
Chinese Journal of Radiation Oncology
1995;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study 18F-deoxyglucose-positron emission tomography and CT fusion (FDG PET) in three dimensional conformal radiotherapy for non-small -c ell lung carcinoma (NSCLC). Methods Gross tumor volume (GTV) of 13 NSCLC patient s were determined by FDG PET and CT separately (GTV PET-CT and GTV CT ), which were then compared. Results Except 2 patients, all the other patients' GTV PET-CT dif fered from their GTV CT. Compared with GTV CT, GTV PET-CT was in creased by an avera ge of 29.2?cm3 in 5 patients and decreased by an average of 41.6?cm3 in 6 patien ts. Conclusions 18F-deoxyglucose-positron emission tomography, which can improve target definition between benign and malignant lesions in the lung, is proved t o be more sensitive and specific in detecting mediastinal lymph node involvement . FDG PET may provide accurate target definition and improve the local control.