Effect of valasartan on the plasma level of calcitonin gene-related peptide in patients with essential hypertension
- VernacularTitle:缬沙坦对高血压病患者血浆降钙素基因相关肽水平的影响
- Author:
Wei SUN
;
Wenying JIN
;
Yongzhen ZHANG
- Publication Type:Journal Article
- Keywords:
hypertension;
calcitonin gene-related peptide;
valasartan
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of valasartan, an angiotensin Ⅱ type 1 (AT 1) receptor antagonist, on the plasma levels of calcitonin gene-related peptide (CGRP) in patients with essential hypertension. Methods 29 outpatients with essential hypertension were treated with valasartan 80mg/day for 6 weeks. 28 age-matched normal blood pressure people were taken as controls. The plasma levels of CGRP were measured in all patients before and after treatment and in controls. Results The plasma levels of CGRP in hypertensive patients were significantly lower than those in controls (minimal value: 0.00 vs 39.95pg/ml; maximal value: 24.07 vs 155.59pg/ml; P
