Performance Measurement of Siemens Inveon PET Scanner for Small Animal Imaging.
- Author:
A Ram YU
1
;
Jin Su KIM
;
Kyeong Min KIM
;
Young Sub LEE
;
Jong Guk KIM
;
Sang Keun WOO
;
Ji Ae PARK
;
Hee Joung KIM
;
Gi Jeong CHEON
Author Information
1. Molecular Imaging Research Center, Korea Institute Radiological and Medical Science, Seoul, Korea. kjs@kirams.re.kr
- Publication Type:Original Article
- Keywords:
NEMA;
Small-animal PET;
Performance measurement
- MeSH:
Aluminum;
Animals;
Mice;
Rats
- From:Korean Journal of Medical Physics
2010;21(2):145-152
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Inveon PET is a recently developed preclinical PET system for small animal. This study was conducted to measure the performance of Inveon PET as recommended by the NEMA NU 4-2008. We measured the spatial resolution, the sensitivity, the scatter fraction and the NECR using a F-18 source. A 3.432 ns coincidence window was used. A 1 mm3 sized F-18 point source was used for the measurement of spatial resolution within an energy window of 350~625 keV. PET acquisition was performed to obtain the spatial resolution from the center to the 5 cm offset toward the edge of the transverse FOV. Sensitivity, scatter fraction, and NECR were measured within an energy window of 350~750 keV. For measuring the sensitivity, a F-18 line source (length: 12.7 cm) was used with concentric 5 aluminum tubes. For the acquisition of the scatter fraction and the NECR, two NEMA scatter phantoms (rat: 50 mm in diameter, 150 mm in length; mouse: 25 mm in diameter, 70 mm in length) were used and the data for 14 half-lives (25.6 hr) was obtained using the F-18 line source (rat: 316 MBq, mouse: 206 MBq). The spatial resolution of the F-18 point source was 1.53, 1.50 and 2.33 mm in the radial, tangential and axial directions, respectively. The volumetric resolution was 5.43 mm3 in the center. The absolute sensitivity was 6.61%. The peak NECR was 486 kcps @121 MBq (rat phantom), and 1056 kcps @128 MBq (mouse phantom). The values of the scatter fraction were 20.59% and 7.93% in the rat and mouse phantoms, respectively. The performances of the Inveon animal PET scanner were measured in this study. This scanner will be useful for animal imaging.
