Alterations of ion channels in cerebrovascular smooth muscle cells during hypert ension
- VernacularTitle:高血压发展过程中脑血管平滑肌细胞离子通道的变化
- Author:
Xiaolian SHI
;
Yongyuan GUAN
- Publication Type:Journal Article
- Keywords:
cerebrovascular;
smooth muscle cells;
hypertension;
potassium channels;
calcium channels;
chloride channels
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Cerebrovascular remodeling is the most important pathologic change during hypertension. Stroke induced by hypertension is threatening thousands of people's lives. The ion channels in cerebrovascular smooth muscle cells may be altered during hypertension and thus the abnormality of cytosolic ion concentration can accelerate cerebrovascular remodeling. These channels, including potassium channels, calcium channels and chloride channels, may play an important role in the cerebrovascular remodeling during hypertension.
