The effects of enteral nutrition with recombinant human growth hormone onimmunological function and inflammatory responses in severe burned rats
- VernacularTitle:肠内营养联合生长激素对烫伤大鼠免疫功能和炎症反应的影响
- Author:
Chen CAI
;
Guanghua GUO
;
Guohu LI
- Publication Type:Journal Article
- Keywords:
Enteral nutrition;
Burn;
rhGH;
Rat
- From:
Parenteral & Enteral Nutrition
1997;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of enteral nutrition with recombinant human growth hormone (rhGH) on immunological function and inflammatory responses in severe burned rats. Methods: Sixty-four SD rats inflicted by 30% TBSA Ⅲ degree scalds were randomly divided into enteral nutrition with rhGH (ENGH) and enteral nutrition (EN) groups. Two groups animal were fed isocaloric enteral nutrition. Lymphocyte subsets, serum albumin, transferrin, serum levels of immunoglobulins,endotoxin,IL-6,TNF-? were determined on the 1st,4th,7th and 10th day postburn. Results: There were significant postburn changes in inflammatory responses, immunological variables in both groups.CD3 + 、CD4 + 、CD4 + /CD8 + in ENGH group were higher(P
