The Effect of D-methionine on Gastric Cancer
- VernacularTitle:右旋甲硫氨酸对胃癌细胞作用初探
- Author:
Jihong LIU
;
Weixin CAO
;
Yubao JI
;
Yi ZHANG
;
Bingya LIU
;
Zhenggang ZHU
;
Min YAN
;
Yanzhe LIN
- Publication Type:Journal Article
- Keywords:
D-methionine;
Gastric cancer;
Apoptosis;
Cell cycle
- From:
Parenteral & Enteral Nutrition
1997;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: To study the effect of D-methionine on gastric cancer and its mechanism. Methods: We used a medium with D-methionine to culture six gastric cancer cell lines. The medium with L-methionine acted as control to culture cells. The proliferation of cells was detected by MTT. Apoptotic rates and cell cycle were detected by FMC. Results: Absorbance of all cell lines was significantly lower than control (P0.05). KATO-Ⅲ cells stayed more in G 0 /G 1 phase (P