Microscopic and ultrastructural observation of primary pulmonary cryptococcosis
- VernacularTitle:原发性肺隐球菌病的光镜和超微结构观察
- Author:
Kang CHEN
- Publication Type:Journal Article
- Keywords:
cryptococcosis;
ultrastructure;
lung
- From:Journal of Third Military Medical University
1983;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the ultrastructural features of primary pulmonary cryptococcosis (PC) and its roles in the pathologic diagnosis. Methods Two cases of PC were observed by light and electron microscopy and histochemical staining. Results The histopathological examination found cryptococcosis granuloma formation in the 2 cases, and the cryptococcous neoformans (CN) were detected in mucicarmine (MC), periodic acid-Schiff (PAS), and Grocot's methenamine-silver (GMS), respectively. Electron microscopy revealed that most of CN had a simple structure and a few organells. The cell wall, cytoplasm, and capsule could be seen, and part of them had nuclei. Conclusion The ultrastructure of CN is simple. Electron microscopic observation is helpful for the correct diagnosis and differential diagnosis of PC.
