Expression of vascular endothelial growth factor and microvascular density in pancreatic carcinoma, and their clinical significance
- VernacularTitle:胰腺导管癌组织中VEGF表达和肿瘤微血管计数的临床意义
- Author:
Fubin ZHANG
;
Bing ZHU
;
Chenhao SHAO
- Publication Type:Journal Article
- Keywords:
pancreatic carcinoma;
vascular endothelial growth factor;
microvessel density;
immunohistochemistry;
prognosis
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of VEGF and microvascular density (MVD) in pancreatic carcinoma and their prognostic value. Methods The protein expression of VEGF and MVD were determined with immunohistochemistry in 48 cases of pancreatic ductal carcinomas, which were surgically resected and pathologically confirmed. Results In 64.6% of pancreatic carcinomas the expression of VEGF was positive, and it was significantly higher than that of normal pancreatic tissues (P