Expression regulation of nicotinic acetylcholine receptor subtype and its physiological significance
- VernacularTitle:烟碱型乙酰胆碱受体亚型的表达调控及其生理意义
- Author:
Yingfan ZHANG
;
Hua JIANG
;
Zihao LIN
- Publication Type:Journal Article
- Keywords:
nicotinic acetylcholine receptor;
subtype;
gene expression and regulation
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Nicotinic acetylcholine receptors concentrate on the postsynaptic membrane in the neuromuscular junction and participate in the neuromuscular transmission,which is of great importance to normal muscle function. The nicotinic acetylcholine receptor is a kind of pentamer.There are 2 types of nicotinic acetylcholine receptor due to the different subunit:fetal type ?-AChR (? 2???) and adult type ?-AChR(? 2???). This article reviews the difference of 2 types of nAChR in expression period,distribution,regulation mechanism and physiological significance.
