The changes and clinical significance of plasma levels of vasoactive substances in patients with congestive heart failure
- VernacularTitle:充血性心力衰竭患者血管活性物质变化的临床意义
- Author:
Ping ZHONG
;
Zhiliang LI
;
Chaoshu TANG
- Publication Type:Journal Article
- Keywords:
Congestive heart failure Vasoactive substances Urotensin Ⅱ Proadrenomedullin N terminal 20 peptide Atrial natriuretic peptide
- From:
Chinese Journal of Practical Internal Medicine
2003;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of plasma urotensinⅡ(UⅡ)、PAMP(proadrenomedullin N-terminal peptide)and ANP(atrial natriuretic peptide)levels in patients with congestive heart failure (CHF) and to illustrate clinical significance of these changes.Methods 52 patients with CHF and 20 age and gender-matched control subjects were studied.Plasma UⅡ.PAMP and ANP levels of 52 patients with CHF and 20 control subjects were measured by radioimmunoassay.Heart function of all study subjects were mensurated by ultrasound cardiography.Results The plasma UⅡ levels were significantly lower in patients with CHF than that in control subjects [(1.48?1.05) vs (4.28?1.21) pg?mL -1,P
