Preliminary study on hypoxic-ischemic encephalopathy in neonates with diffusion-weighted MR imaging
- VernacularTitle:用MR扩散加权成像评价新生儿缺氧缺血性脑病的初步研究
- Author:
Xiaoming WANG
;
Liying CHEN
;
Nan LIN
;
Qiyong GUO
- Publication Type:Journal Article
- Keywords:
Hypoxia, brain;
Infant, newborn;
Magnetic resonance imaging
- From:
Chinese Journal of Radiology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate hypoxic-ischemic encephalopathy (HIE) in neonates with diffusion-weighted MR imaging, and to explore the value and limitation of diffusion-weighted imaging (DWI) compared with conventional magnetic resonance imaging.Methods Conventional magnetic resonance T 1-weighted imaging (T 1WI) and DWI (b=700 s/mm2) were performed in 36 neonates with HIE ( average age, 8.44 days; range, 3 hours to 22 days ), and the cortex and subcortical white matter, deep white matter, basal ganglia and thalamus, cerebral ventricle, and extra-cerebral interspace etc were observed.Results Signal abnormalities were shown on DWI with hypoxic-ischemic insults, which included diffuse brain damage (19.4%, 7/36): extensive high signals in the regional cortex, subcortical and deep white matter; localized brain damage: high signals along lateral ventricular wall and triangular part (27.8%, 10/36 ), and punctate high signals in the frontal deep white matter (5.6%, 2/36).On T 1WI, the incidence of the corresponding changes were 16.7% (6/36), 36.1% (13/36), and 30.6%(11/36), respectively.Hemorrhagic lesions demonstrated high signals on T 1WI and no signals on DWI.Conclusion DWI was applicable for acute HIE, and T 1WI was suitable for subacute and chronic HIE.
