VEGFR-3 expression in esophageal carcinoma and its significance
- VernacularTitle:VEGFR-3在食管鳞癌中的表达及意义
- Author:
Huiwen MA
;
Houjie LIANG
- Publication Type:Journal Article
- Keywords:
esophageal carcinoma;
immunohistochemistry;
VEGFR-3;
prognosis
- From:Journal of Third Military Medical University
2003;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate of the expression of vascular endothelial growth factor receptor 3 (VEGFR-3) and its relationship with the prognosis of esophageal carcinoma. Methods VEGFR-3 in 156 cases of esophageal carcinoma tissues was detected by immunohistochemistry. The follow-up data for 3 years in 47 cases were analyzed. Results The VEGFR-3 expression in esophageal carcinoma tissues with lymph node metastasis was higher than that in those without lymph node metastasis. VEGFR-3 expression was associated with the clinicopathological stages. Analysis of the follow-up data also showed that there was a statistically positive correlation between VEGFR-3 expression and lymph node metastasis in primary tumors (P
