Advances in the research on homo sapiens cytochrome P450 2J2
- VernacularTitle:人类细胞色素酶P4502J2的研究进展
- Author:
Chenhui LUO
;
Honghao ZHOU
- Publication Type:Journal Article
- Keywords:
cytochrome P450;
CYP2J2;
EETs
- From:
Chinese Pharmacological Bulletin
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
For many years, researches on Cytochrome P450 had been focused on their roles in exogenous drugs and poisons metabolism. In fact, Cytochrome P450 also showed significant importance in conversion of endogenous materials, such as steroids, cholesterol, hormones, fatty acid and vitamins. Among such Cytochrome P450 enzymes, CYP2J2 mainly metabolizing arachidonic acids into epoxyeicosatrienoic acids, was detected recently in human beings. The association of CYP2J2 with diseases attracts many researchers great interests. This article briefly summarized those researches of homo sapiens CYP2J2 on its distribution, physical significance, coding gene and mutants of gene as well.
