Comparison of effects of moxonidion and clonidine on decreasing blood pressure in spontaneous hypertensive rats
- VernacularTitle:莫索尼定与可乐定对自发性高血压大鼠作用的比较
- Author:
Wei ZHANG
;
Weizhong ZHU
;
Jinghua HUANG
- Publication Type:Journal Article
- Keywords:
moxonidine;
clonidine;
SHR;
hypertension;
antihypertensive dr ug
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). CONCLUSION: The effects of 10 mg?kg -1 m oxonidine on reduced blood pressure and heart rate in SHR is equal to the effect s of 1 mg?kg -1 clonidine after once large dose oral administration. T here is no significant difference between the moxonidine and clonidine of the sa me dose in reducing blood pressure after repeatedly small dose oral administrati on in SHR.
