Measurement of glomerular filtration rate with renal dynamic imaging:comparison with two-sample method
- VernacularTitle:肾动态显像法与双血浆法测定肾小球滤过率的对比分析
- Author:
Chunli ZHANG
- Publication Type:Journal Article
- Keywords:
Glomerular filtration rate;
Renal artery/radionuclide;
two-sample method
- From:
Journal of Peking University(Health Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the estimation of glomerular filtration rate(GFR)by renal dynamicimaging with that estimated by two-sample method and evaluate the reliability of measurement of GFR byrenal dynamic imaging.Methods:The study was performed in 54 patients(33 males and 21 females;aged 15 to 82 years)with primary or secondary chronic nephrosis.The patients were intravenously bolusinjected with 185 MBq/1 mL of (99)~Tc~m-DTPA 20 min after drinking 300 mL of water.Renal dynamic ima-ging was performed and the image was processed according to standard procedure(Gates' method)to ob-tain GFR.3mL of blood was withdrawn 2h and 4h postinjection,respectively,and radioactivity of 1mLplasma was measured.GFR was calculated by the formula of two-sample method.The correlation ofGFRs measured by renal dynamic imaging and by two-sample method was analyzed using regression anal-ysis.The correlations of GFRs determined by the two methods with urea and creatinine were also meas-ured.Results:The GFR measured by renal dynamic imaging was slightly lower than that measured bytwo-sample method.Excellent correlation was obtained by two methods with r=0.881 5 and P
