Effect of aspirin on plasma levels of nitric oxide and alpha-granule membrane protein in patients with acute cerebral infarction
- VernacularTitle:阿司匹林对急性脑梗死患者血浆一氧化氮及血小板?颗粒膜蛋白的影响
- Author:
Dan WANG
;
Haojia ZHU
;
Zhuohui LIANG
- Publication Type:Journal Article
- Keywords:
Aspirin Cerebral infarction Nitric oxide Alpha-granule membran
- From:
Chinese Journal of Practical Internal Medicine
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore effect of aspirin on plasma levels of nitric oxide (NO) and alpha-granule membrane (GMP-140) protein in patients with acute cerebral infarction.Methods 78 patients with acute cerebral infarction were randomly divided into the aspirin group (40 cases) and the control group (38 cases).Plasma NO and GMP-140 were determined by the method of nitrate reductase and enzyme-linked immunosorbent assay in aspirin group and controls at moment of hospitalization and after two weeks.Results Plasma NO and GMP-140 of aspirin group after aspirin treatment were statistically lower than those of controls (P