Expressions of CD44 and transforming growth factor-?_1 in endometrium and ectopic endometrial tissues in endometriosis patients
- VernacularTitle:子宫内膜异位症患者宫内膜异位内膜组织中CD44、TGF-?_1的表达
- Author:
Chanyu ZHANG
;
Changxu SHI
- Publication Type:Journal Article
- Keywords:
endometriosis;
CD44;
transforming growth factor-? 1;
immunohistochemistry
- From:Journal of Third Military Medical University
2003;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore relationship of CD44 and transforming growth factor-? 1 (TGF-? 1) in endometriosis (EM) patients. Methods The histopathological changes and the expressions of CD44 and TGF-? 1 were observed and determined by immunohistochemistry in 17 cases of ectopic endometrium of EM patients and 17 cases of ovarian ectopic endometrium of EM patients. The other 20 cases of non-endometriosis and non-tumorous endometrial tissues were used as the control group. Results No difference in the expressions of CD44 and TGF-? 1 was found in the ectopic endometrium of EM patients and the control group, but the expressions in the ovarian ectopic endometrium of EM patients were significantly higher than those in the control group. Conclusion The abnormal expressions of CD44 and TGF-? 1 in ectopic endometrium of EM patients may be associated with the genesis and progression of EM.
