Effect of SNP on GFAP synthesis with immunofluorescent method in hippocampus
- VernacularTitle:用免疫荧光法探讨硝普钠对海马区胶质纤维酸性蛋白合成调节的影响
- Author:
Jingjun ZHANG
;
Xincheng WANG
;
Xinquan JIANG
- Publication Type:Journal Article
- Keywords:
sodium nitroprusside;
hippocampus;
cGMP;
glial fibrilla ry acidic protein
- From:
Chinese Pharmacological Bulletin
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To observe the effect of sodium nitrop russide (SNP)on glial fibrillary acidic protein(GFAP) synthesis in the gerbil hippocampus. Method lmmunofluorescent histochemical staining method was used. Result SNP increased GFAP synthesis in rediatum layer,molecular layer and dentate gyrus.There were not GFAP positive cells in rediatum layer and mol ecular layer.Number of GFAP positive cells related to dose of SNP.Conclu sion SNP increased GFAP synthesis.
