Relationship between nitration and oxidation related enzymes iNOS,COX-2 and hematological malignancies
- VernacularTitle:硝基化和氧化相关酶类iNOS和COX-2与血液系统恶性肿瘤
- Author:
Lieping GUO
- Publication Type:Journal Article
- Keywords:
nitric oxide synthase,inducible;
cyclooxygenase-2;
hematological malignances
- From:
Academic Journal of Second Military Medical University
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Inducible nitric oxide synthase(iNOS) and cyclooxygenase-2(COX-2) are nitration and oxidation related enzymes, and their correlations with tumors have been drawing more and more attention.There are 2 different viewpoints on the correlation between the 2 enzymes and hematological malignances,and their functioning mechanisms are still unclear.The selective inhibitors of NOS,COX,or the both may provide a new approach for the treatment of hematological malignancies.
