Angiogenesis in rheumatoid arthritis
- VernacularTitle:类风湿关节炎中血管生成的分子机制
- Author:
Li WU
;
Wei WEI
- Publication Type:Journal Article
- Keywords:
rheumatoid arthritis;
angiogenesis;
cell proliferation;
endothelial growth factor
- From:
Chinese Pharmacological Bulletin
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Indices of angiogenesis are increased in synovia from patients with rheumatoid arthritis, and vascu-lar proliferation may contribute to the pathogenesis of synovitis, pan nus growth, bone and cartilage destruction, and osteophyte formation. Many proan giogenic factors are expressed in the synovium in RA. They have been shown to ha ve important effects in the angiogenic process in RA. So the blockade of angioge nesis appears to be a promising avenue for the future treatment of RA.
