Effects of growth hormone on perioperative obstructive jaundice rats
- VernacularTitle:生长激素在梗阻性黄疸大鼠围手术期应用的意义
- Author:
Jianyong ZHU
;
Ping BIE
;
Yingguo CHEN
- Publication Type:Journal Article
- Keywords:
obstructive jaundice;
growth hormone
- From:Journal of Third Military Medical University
2003;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of recombinant human growth hormone (rhGH) applied perioperatively on the surgical tolerance, safety, and recovery in obstructive jaundice (OJ) rats. Methods A total of 146 Wistar male rats were randomly divided into five groups: SHAM, CBDL, REF, CBDL-GH, and REF-GH. rhGH was injected subcutaneously at the dose of 0.5 u/kg per day. One-week mortality was observed. Liver function indices, prealbumin (PA), TNF-?, and urine DBIL were measured. Results One-week mortality in REF-GH group was much lower than that in REF group (P
