Relationship between hTERT expression in human gastric carcinoma and its precancerous lesions and Helicobacter pylori infection
- VernacularTitle:胃癌前病变组织和胃癌中hTERT的表达及其与幽门螺杆菌感染的关系
- Author:
Guoan WANG
;
Haifeng LIU
;
Dianchun FANG
- Publication Type:Journal Article
- Keywords:
gastric cancernoma;
precancerous lesion;
Helicobacter pylori;
telomerase;
human telomerase catalytic subunit
- From:Journal of Third Military Medical University
2003;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of hTERT in human gastric carcinoma and its precancerous lesions and to explore the relationship between hTERT expression and Helicobacter pylori (Hp) infection. Methods hTERT expression was detected by immunohistochemical method. Hp was detected by rapid urease test and Warthin-Starry silver staining. Results The expression level of hTERT in human gastric carcinoma (78.95%) was significantly higher than that in gastric dysplasia (64.29%), in intestinal metaplasia (46.67%), and in atrophic gastritis (25.00%, P
