Change in nitriergic nerves in myenteric plexus in gastric antrum of diabetic rats
- VernacularTitle:糖尿病大鼠胃窦肌间神经丛氮能神经的变化及其意义
- Author:
Qinglin LONG
;
Dianchun FANG
;
Hongtao SHI
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
abnormality of nerve function;
nitriergic nerves;
electrogastrography
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of nitriergic nerves in the myenteric plexus of the gastric antrum in diabetic rats with motor disorder. Methods Rats were randomly divided into diabetic group and control group. Electrogastrogram was recorded, and the number of cholinergic nerves in the myenteric plexus of the gastric antrum was counted 3 months after reproducing diabetes in the model group. Results In the rats of diabetic group, gastro-electric dysrhythmia was observed more frequently, and the number of nitriergic cells in the myenteric nerves was significantly decreased compared with control group. Conclusion The changes in nitriergic nerves in the myenteric plexus of the gastric antrum might be one of the mechanisms of gastro-electric dysrhythmia and gastric motility disorders in diabetic rats.