Mechanism of cisapride in the treatment of gastric eletro-dysrhythmia
- VernacularTitle:西沙必利治疗胃电节律失常机制的实验研究
- Author:
Jingjing ZHAO
;
Zhenhua WANG
;
Dianchun FANG
- Publication Type:Journal Article
- Keywords:
cisarpride;
gastricelectric dysrythmia;
treatment
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mechanism of cisapride in the treatment of gastricelectric dysrhythmia. Methods Cisarpride was gavage fed to rats in which gastricelectric dysrhythmia hed been reproduced. The cholinergic and nitriergic nerves in myenteric plexus of gastric antrum were examined with histochemical staining methods and whole mount preparation technique. The levels of cAMP and cGMP in the antral smooth muscle were measured by radioimmunoassay. Results Gastricelectric dysrhythmia in the model group was ameliorated after the treatment with cisapride(P
