Effects of dexamethasone on cell apoptosis in pulmonary tissues in rats after tail-suspension simulating weightlessness
- VernacularTitle:地塞米松对尾悬吊大鼠肺组织细胞凋亡的影响
- Author:
Congjun HAO
;
Changting LIU
;
Junfen WANG
- Publication Type:Journal Article
- Keywords:
weightlessness simulated;
apoptosis;
pulmonary tissues;
dexamethasone
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of dexamethasone on prevention of apoptosis in pulmonary tissues of rats after simulated weightlessness. Methods Tail suspension was used to simulate weightlessness. Thirty Sprague-Dawley male rats were divided randomly into 3 groups: control group, tail suspension for 7 days group, and dexamethasone treatment after suspension group. TUNEL technique was used to detect cell apoptosis in pulmonary tissues. Results The rate of apoptotic cells in the lung of rats suspended for 7 day was higher than that of control group(P
