Study on the level of MDA and SOD in cerbrospinal fluid from patients with cysticercosis.
- VernacularTitle:脑囊虫病患者脑脊液中丙二醛、超氧化物歧化酶检测及意义
- Author:
Like WU
;
Danqing DUAN
;
Lichun ZHOU
- Publication Type:Journal Article
- Keywords:
Cerebral cysticercosis;
Superoxide dismutase (SOD);
Malondialdehyde(MDA)
- From:
Chinese Journal of Practical Internal Medicine
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
ObJective To measure the level of MDA and SOD in cerebrospinal fluid from patients with cysticercosis indifferent stages and to investigate their effects on this dieases. Methods Forty-nine patients with a single cysticercus incerebral parenchyma and twenty normal controls parlticipated in the study. According to the magnetic resonance imaging(MRI) results, patients were divided into four stages. The level of MDA,SOD in CSF were tested. The data were analyzedwith the software of SPSS. Results The amount of SOD was significantly decreased in all stages except the fourth stage,while the level of MDA was increased in all the stages,and reached its peak in the second stage. There was a negative cor-relation between SOD and MDA. Conclusion The data suggested oxygen free radicals may be a main mechanism of para-site killing.
