Clinical and electromyography analysis of 46 cases of adult spinal muscular atrophy.
- VernacularTitle:成人型脊髓性肌萎缩症46例临床分析
- Author:
Chuanwen ZHANG
;
Xiaojun HE
;
Ping ZHANG
- Publication Type:Journal Article
- Keywords:
Adult spinal muscular atrophy;
Clinical;
Electromyography;
Pathomorphism
- From:
Chinese Journal of Practical Internal Medicine
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical, electromyography and muscular pathological feature in adult spinalmuscular atrophy (SMA_4). Methods The clinical and electromyography and pathological materials from 48 patients withSMA_4. were studied in retrospect tively. Results SMA_4 onset was averaged 38.23 years old,The disease showed proximalweakness and atrophy. The electromyoguphy in the patients with SMA_4. presented as abnormal insertion potential,fibrilla-tion potential and fascicular potential, positive spike in some patients, remarkable increase of mean amplitude, mean timelimit and polyphasic action potential,and so on. Muscle biopsy showed: 1. small groups atrophy mainly;2. extensive fibertype grouping and more hypertrophic fiber. Conclusions SMA_4 could be diagnosed by the clinical manifestations andelectromyography and muscle biopsy.
