Induction mechanism and research progress of CYP2C9
- VernacularTitle:细胞色素氧化酶CYP2C9的诱导机制及研究进展
- Author:
Xiaohong DUAN
;
Honghao ZHOU
- Publication Type:Journal Article
- Keywords:
CYP2C9;
polymorphism;
allelic variants;
pharmacogenetics
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
CYP2C9 is an important enzyme of drug metabolism expressed in liver, It can metabolize several clinically important drugs, some with a low therapeutic index. This review summarizes the CYP2C9 gene structure, induction mechanism, known polymorphism and functional significances and their population frequencies.
