Role of leptin in the pathogenesis of liver disease and molecular mechanism of leptin's effects
- VernacularTitle:瘦素在肝脏疾病中的作用和分子机制
- Author:
Qi CAO
;
Jun LI
- Publication Type:Journal Article
- Keywords:
leptin;
fatty liver;
hepatitis;
hepatic fibrosis;
hepatic cirrhosis;
NASH
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
This review summarized the current progress in the pathogenesis of leptin-mediated liver disease including fatty liver, hepatitis,fibrosis or cirrhosis. Analysis of leptin effect on activation of hepatic Kupffer cells and hepatic stellate cells was made and molecular mechanism and signal pathways were also discussed.
