Research on relation between genotype and effect of lamivudine in patient with hepatitis B virus infection
- VernacularTitle:乙型肝炎病毒基因型与拉米夫定治疗效应关系研究
- Author:
Honghe ZHANG
;
Tingjun SHAO
;
Zhongguo YANG
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
genotype;
lamivudine;
efficacy;
genotype
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). After lamivudine treatment, the rate of the transform negative of HBV DNA in genotype C was significantly higher than that in genotype B, and the rate of the bounce of HBV DNA in genotype B was higher than that in genotype C (P 0.05). CONCLUSION: There may be a relation between the effect of lamivudine and the genotype of Hepatitis B virus. The effect of the lamivudine treatment may be better in the patients with genotype C.